Query   'Dynein light chain type 1'  matched   8 Records

Record No : 1

Instance ID10303
Regular Expression[^P]x[KR]xTQT
Motif InstanceLHRSTQT
Bait Uniprot AccessionQ15326
Bait Uniprot IdentifierZMY11_HUMAN
Bait Gene NameZMYND11
Bait OrganismHomo sapiens (Human)
Sequence Position411-417
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down; Y2H; Sequence based prediction
Interaction ID20303
Interacting DomainDynein light chain type 1
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11148209
CommentsDynein (Light Chain) binding KxTQT motif in human Zinc finger MYND domain-containing protein BS69 that binds to DLC-8 (highly conserved 8-kDa light chain of Dynein)

Record No : 2

Instance ID10304
Regular Expression[^P]x[KR]xTQT
Motif InstanceYTKETQT
Bait Uniprot AccessionQ13409
Bait Uniprot IdentifierDC1I2_HUMAN
Bait Gene NameDYNC1I2
Bait OrganismHomo sapiens (Human)
Sequence Position156-162
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography
Interaction ID20304
Interacting DomainDynein light chain type 1
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17551010
CommentsDynein (Light Chain) binding KxTQT motif in human Cytoplasmic dynein 1 intermediate chain 2 that binds to DLC-8 (highly conserved 8-kDa light chain of Dynein)

Record No : 3

Instance ID10305
Regular Expression[^P]x[KR]xTQT
Motif InstanceYTKQTQT
Bait Uniprot AccessionQ24246
Bait Uniprot IdentifierDYIN_DROME
Bait Gene Namesw
Bait OrganismDrosophila melanogaster (Fruit fly)
Sequence Position128-134
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography; NMR
Interaction ID20305
Interacting DomainDynein light chain type 1
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)17570393
CommentsKxTQT-motif in Drosophila Cytoplasmic dynein 1 intermediate chain/ Protein short wing (sw) that binds to Drosophila LC8 (ctp)

Record No : 4

Instance ID10306
Regular Expression[^P]x[KR]xTQT
Motif InstanceCDKSTQT
Bait Uniprot AccessionO43521
Bait Uniprot IdentifierB2L11_HUMAN
Bait Gene NameBCL2L11
Bait OrganismHomo sapiens (Human)
Sequence Position110-116
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)NMR; Y2H; Overlapping binding peptide; Pull down
Interaction ID20306
Interacting DomainDynein light chain type 1
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11178896, 11148209
CommentsDynein (Light Chain) binding KxTQT motif in human Bcl-2-like protein 11 (BCL2L11)/ Bcl2-interacting mediator of cell death (BIM) that binds to DLC-8

Record No : 5

Instance ID10307
Regular Expression[^P]x[KR]xTQT
Motif InstanceSAKATQT
Bait Uniprot AccessionP40688
Bait Uniprot IdentifierSWA_DROME
Bait Gene Nameswa
Bait OrganismDrosophila melanogaster (Fruit fly)
Sequence Position289-295
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Sequence based prediction; Y2H; Co-IP; Pull down; Western blot; X-ray crystallography; NMR
Interaction ID20307
Interacting DomainDynein light chain type 1
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11148209, 10783235, 17570393
CommentsKxTQT-motif in Drosophila Protein swallow (swa) that binds to Drosophila LC8 (ctp)

Record No : 6

Instance ID10308
Regular Expression[^P]x[KR]xTQT
Motif InstanceEDKSTQT
Bait Uniprot AccessionP22363
Bait Uniprot IdentifierPHOSP_RABVC
Bait Gene NameP
Bait OrganismRabies virus (strain CVS-11) (RABV)
Sequence Position142-148
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis
Interaction ID20308
Interacting DomainDynein light chain type 1
Disease Association(s)Rabies
Inhibitor(s)Unknown
Reference(s)17438267
CommentsThe dynein light chain 8 binding motif of rabies virus phosphoprotein that binds to mouse DLC-8, the interaction being essential for RV pathogenesis

Record No : 7

Instance ID10309
Regular Expression[^P]x[KR]xTQT
Motif InstanceYSKETQT
Bait Uniprot AccessionO88485
Bait Uniprot IdentifierDC1I1_MOUSE
Bait Gene NameDync1i1
Bait OrganismMus musculus (Mouse)
Sequence Position149-155
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; NMR; Pull down; Competition binding; CD
Interaction ID20309
Interacting DomainDynein light chain type 1
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11148209
CommentsThe dynein light chain 8 binding motif of mouse Cytoplasmic dynein 1 intermediate chain 1 that binds to mouse DLC-8

Record No : 8

Instance ID10310
Regular Expression[^P]x[KR]xTQT
Motif InstanceCDKSTQT
Bait Uniprot AccessionO43521
Bait Uniprot IdentifierB2L11_HUMAN
Bait Gene NameBCL2L11
Bait OrganismHomo sapiens (Human)
Sequence Position50-56
Critical ResiduesP2; P4; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Co-IP; Mutation analysis
Interaction ID20310
Interacting DomainDynein light chain type 1
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10198631, 12591950
CommentsDynein (Light Chain) binding KxTQT motif in Isoform Bim(L) of human Bcl-2-like protein 11 (BCL2L11)/ Bcl2-interacting mediator of cell death (BIM) that binds to DLC-8 to neutralize its antiapoptotic activity




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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)